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VSL#3

The #1 gastroenterologist-recommended multi-strain probiotics brand

Intended for the dietary management of IBS, ulcerative colitis, and pouchitis. Ultra-high-potency and comprised of 8 complementary strains, VSL#3 helps restore and maintain microbiome balance.

VSL Probiotics: ALegacy of Science in Every Strain.

Trusted worldwide

A legacy built on trust andexpertise.

Rooted in science

Guided by probiotic research.

Commitment to quality

Ensuring potency and reliability.

Designed for diverse needs

Supporting gut and women's health.

VSI#3 A Gold Standard in Probiotics

  • A powerful probiotic medical food
  • The #1 gastroenterologist-recommended multi-strain probiotic sbrand
  • Ultra-high-potency - guaranteed through expiration when stored as recommended.
  • 8 complementary probiotic strains from 3 different genera.
  • Used in clinical practice and supported by clinical and scientific research.

Science Over Hype. Purpose Over Promises.

Built on the legacy of VSL#3 — a probiotic trusted by healthcare professionals and recognized for its scientific rigor - VSL Probiotics continues to advance microbiome science through targeted, high-quality formulations that support both clinical dietary management and everyday wellness

Designed for Viability

Carefully designed formulations that help safeguard live bacteria from production to delivery.

Committed to Potency

Potent probiotic formulations guaranteed to maintain labeled CFU counts through expiration.

Science-Led Strain Selection

Thoughtfully formulated with complementary probiotic strains chosen for function and purpose.

A Legacy of Expertise

A probiotic heritage recognized for its consistency, credibility, and professional trust.

Clean Ingredients. Trusted Standards.

Dairy-Free

Gluten-Free

Soy-Free

Nut-Free

Vegan

No GMOs

The VSL Probiotics Difference

Medical Foods & Supplements

From medical foods formulated for the dietary management of Gl conditions to supplements for daily wellness, VSL Probiotics is made to the highest standards of quality and consistency.

Proven Potency

Up to 900 billion live bacteria per serving — verified to maintain labeled CFU counts through expiration when stored as recommended.

Evidence-Based Formulations

Formulated with probiotic strains and combinations supported by published research and guided by microbiome science.

Trusted by Professionals

Rooted in the heritage of VSL#3 — a probiotic trusted by healthcare professionals—VSL Probiotics carries that same dedication to quality and research into every new formulation.

VSL#3 Capsules are an ultra-high-potency probiotic medical food formulated to support the dietary management of IBS and ulcerative colitis. Each capsules provides 112.5 billion live bacteria from 8 clinically studied probiotic strains working together.

It's What's on the Inside

Our unique 8-strain formulation is designed so each strain complements the others, helping maintain a balanced gut microbiota. Billions of live, beneficial bacteria work together to support digestive health.

Bifidobacterium

Bifidobacterium breve, Bifidobacterium lactis (previously classified as B. infantis), Bifidobacterium lactis (previously classified as B. longum)

Lactobacillus

Lactobacillus acidophilus, Lactobacillus helveticus (previously classified as L. delbrueckii subsp.bulgaricus), Lactobacillus paracasei,
Lactobacillus plantarum

Streptococcus

Streptococcus thermophilus

FAQs

VSL#3 is an ultra-high-potency probiotic medical food intended for the dietary management of irritable bowel syndrome (IBS), ulcerative colitis (UC), and an ileal pouch (pouchitis).

VSL#3 should be stored under refrigeration at 36-46°F (2-8°C) to preserve potency. It can remain at room temperature for up to 2 weeks without reducing effectiveness.

Medical foods are formulated for the dietary management of diseases or conditions with distinctive nutritional needs that cannot be met by diet alone. Unlike dietary supplements, medical foods are intended for use under a healthcare provider's supervision.

In a 2021 clinical study, VSL#3 demonstrated dietary management outcomes in people with IBS comparable to those achieved with a low FODMAP diet1 - a commonly recommended but restrictive approach. Because VSL#3 is certified FODMAP Friendly, it can also be used alongside a low FODMAP diet for flexible dietary management.

1Ankerson L, et al. J Med Internet Res. 2021; 23(12): e30291.